Motif ID: POU5F1_SOX2{dimer}.p2
Z-value: 1.371
Transcription factors associated with POU5F1_SOX2{dimer}.p2:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| POU5F1 | 5460 | POU class 5 homeobox 1 |
| SOX2 | 6657 | SRY (sex determining region Y)-box 2 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| POU5F1 | chr6_-_31134614 | 0.59 | 1.7e-02 | Click! |
| SOX2 | chr3_+_181429711 | -0.27 | 3.1e-01 | Click! |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in process category:
Showing 1 to 10 of 10 entries
| Enrichment | P-value | GO Accession | GO Term |
|---|---|---|---|
| 22.47 | 9.88e-03 | GO:0006690 | icosanoid metabolic process |
| 21.17 | 1.25e-02 | GO:0033559 | unsaturated fatty acid metabolic process |
| 18.35 | 2.21e-02 | GO:0006641 | triglyceride metabolic process |
| 17.21 | 2.85e-02 | GO:0006638 | neutral lipid metabolic process |
| 17.21 | 2.85e-02 | GO:0006639 | acylglycerol metabolic process |
| 10.52 | 3.65e-02 | GO:0006869 | lipid transport |
| 8.39 | 1.34e-03 | GO:0032787 | monocarboxylic acid metabolic process |
| 7.92 | 3.42e-02 | GO:0008202 | steroid metabolic process |
| 5.27 | 4.58e-03 | GO:0044255 | cellular lipid metabolic process |
| 5.21 | 6.16e-05 | GO:0006629 | lipid metabolic process |
Gene overrepresentation in compartment category:
Showing 1 to 1 of 1 entries
| Enrichment | P-value | GO Accession | GO Term |
|---|---|---|---|
| 4.16 | 9.51e-03 | GO:0005615 | extracellular space |
Gene overrepresentation in function category:
Showing 1 to 10 of 10 entries
| Enrichment | P-value | GO Accession | GO Term |
|---|---|---|---|
| 274.98 | 3.58e-06 | GO:0047115 | trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity |
| 274.98 | 1.04e-03 | GO:0047026 | androsterone dehydrogenase (A-specific) activity |
| 274.98 | 1.04e-03 | GO:0047718 | indanol dehydrogenase activity |
| 206.24 | 1.43e-05 | GO:0047023 | androsterone dehydrogenase activity |
| 110.00 | 1.04e-02 | GO:0032052 | bile acid binding |
| 39.30 | 4.54e-03 | GO:0016628 | oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor |
| 37.52 | 5.25e-03 | GO:0033764 | steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| 31.75 | 8.77e-03 | GO:0016229 | steroid dehydrogenase activity |
| 11.24 | 3.38e-02 | GO:0008201 | heparin binding |
| 6.86 | 3.67e-04 | GO:0008289 | lipid binding |